BDBM50331774 (S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-trifluoroethylamino)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methylpentanamide::CHEMBL1289764

SMILES CC(C)(F)C[C@H](N[C@@H](c1ccc(-c2cn[nH]c2)cc1)C(F)(F)F)C(=O)N[C@H](C#N)Cc1ccccc1

InChI Key InChIKey=CGAOFGCVDRGRSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331774   

TargetCathepsin F(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331774BDBM50331774((S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-tri...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Cat F expressed in rabbit HIG82 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331774BDBM50331774((S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-tri...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331774BDBM50331774((S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-tri...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human Cat B in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331774BDBM50331774((S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-tri...)
Affinity DataIC50: 379nMAssay Description:Inhibition of human Cat LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed