BDBM50331957 CHEMBL1289893::N-(1-Adamantyl)-5-pyridin-3-yl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyra-zolo[1,5-a]pyrimidine-3-carboxamide

SMILES O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1cccnc1)C[C@@H]2C(F)(F)F

InChI Key InChIKey=VBKRXAWTMUAUFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331957   

TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331957BDBM50331957(N-(1-Adamantyl)-5-pyridin-3-yl-7-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed