BDBM50332491 (E)-3-(5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)thiophen-2-yl)-N-hydroxyacrylamide::CHEMBL1630108
SMILES ONC(=O)\C=C\c1ccc(s1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
InChI Key InChIKey=SUBNLERWESOYMX-YRNVUSSQSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50332491
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of INSR by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of Flag tagged human recombinant HDAC3 expressed in Sf21 cells coexpressing SMRT DAD domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Flag tagged human recombinant HDAC8 expressed in Sf21 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of EGFR by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PLK1 by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PDGFRbeta by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of ABL1 by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of CDK2 by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of HER2 by flash plate based radioactive enzyme assayMore data for this Ligand-Target Pair