BDBM50332544 CHEMBL1630719::N-(4-(4-(5-isopropoxy-5,6-dihydropyrazin-2-yloxy)phenyl)butan-2-yl)acetamide

SMILES CC(=O)NC(C)CCc1ccc(OC2=NCC(OC(C)C)N=C2)cc1

InChI Key InChIKey=OZBDMJFOUOENCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332544   

TargetAcetyl-CoA carboxylase 2(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332544BDBM50332544(N-(4-(4-(5-isopropoxy-5,6-dihydropyrazin-2-yloxy)p...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332544BDBM50332544(N-(4-(4-(5-isopropoxy-5,6-dihydropyrazin-2-yloxy)p...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332544BDBM50332544(N-(4-(4-(5-isopropoxy-5,6-dihydropyrazin-2-yloxy)p...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed