BDBM50332563 CHEMBL1630721::trans-(S)-N-(4-(4-(6-isopropoxypyridin-3-yloxy)phenyl)butan-2-yl)acetamide

SMILES CC(=O)N[C@@H](C)CC[C@H]1CC[C@H](Oc2ccc(OC(C)C)nc2)CC1

InChI Key InChIKey=BGSSITZNPKHFTP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332563   

TargetAcetyl-CoA carboxylase 2(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332563BDBM50332563(trans-(S)-N-(4-(4-(6-isopropoxypyridin-3-yloxy)phe...)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332563BDBM50332563(trans-(S)-N-(4-(4-(6-isopropoxypyridin-3-yloxy)phe...)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332563BDBM50332563(trans-(S)-N-(4-(4-(6-isopropoxypyridin-3-yloxy)phe...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed