BDBM50332625 (R)-2-((1S,3S,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)propan-1-ol::CHEMBL1630783

SMILES C[C@@H]1CC[C@H]([C@@H](C)CO)C[C@@H]1N(C)c1ncnc2[nH]ccc12

InChI Key InChIKey=OTKXTQXJUVNMLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332625   

TargetTyrosine-protein kinase JAK3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332625BDBM50332625((R)-2-((1S,3S,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-tagged human JAK3 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed