BDBM50332642 3,4-difluoro-N-(3-(2-oxo-2-(pyridin-2-yl)acetyl)phenyl)benzamide::CHEMBL1630811

SMILES Fc1ccc(cc1F)C(=O)Nc1cccc(c1)C(=O)C(=O)c1ccccn1

InChI Key InChIKey=VKADJXFVMMMPTO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332642   

TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50332642(3,4-difluoro-N-(3-(2-oxo-2-(pyridin-2-yl)acetyl)ph...)
Affinity DataKi:  1.24E+3nMAssay Description:Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50332642(3,4-difluoro-N-(3-(2-oxo-2-(pyridin-2-yl)acetyl)ph...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50332642(3,4-difluoro-N-(3-(2-oxo-2-(pyridin-2-yl)acetyl)ph...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed