BDBM50334180 2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazolidin-3-yl)acetic acid::2-(5-(3-Phenoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid::2-(5-(3-Phenoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)aceticacid::CHEMBL1172417

SMILES OC(=O)CN1C(=S)S\C(=C/c2cccc(Oc3ccccc3)c2)C1=O

InChI Key InChIKey=NJNBOILPWXEYGR-GDNBJRDFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334180   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  410nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)TBA
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  1.98E+7nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  8.68E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed