BDBM50334189 4-Cyano-N-(pyridin-3-yl)benzamide::CHEMBL1645412

SMILES O=C(Nc1cccnc1)c1ccc(cc1)C#N

InChI Key InChIKey=OMHXOAPLNZOELY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334189   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50: 78nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50: 454nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed