BDBM50334272 CHEMBL1642669::N6-(2,5-dimethoxyphenyl)-9H-purine-2,6-diamine

SMILES COc1ccc(OC)c(Nc2nc(N)nc3nc[nH]c23)c1

InChI Key InChIKey=KJHDASWFKRBDMI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334272   

TargetSerine/threonine-protein kinase B-raf(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50334272(N6-(2,5-dimethoxyphenyl)-9H-purine-2,6-diamine | C...)
Affinity DataKd:  430nMAssay Description:Inhibition of BRAF by high-throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50334272(N6-(2,5-dimethoxyphenyl)-9H-purine-2,6-diamine | C...)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of ASK1 assessed as phosphorylated fluorescent peptide by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed