BDBM50334361 4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide::4-({[2-(1-methylethyl)phenyl]carbamoyl}amino)benzenesulfonamide::4-{([(2'-Isopropylphenyl)amino]carbonyl)amino}benzenesulfonamide::CHEMBL1615280

SMILES CC(C)c1ccccc1NC(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=NCAVVYYIUQIEED-UHFFFAOYSA-N

Data  11 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50334361   

TargetCarbonic anhydrase 9(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 9(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human carbonic anhydrase 2 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCarbonic anhydrase 12(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 1 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  5.61E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334361(4-(3-(2-isopropylphenyl)ureido)benzenesulfonamide ...)
Affinity DataKi:  6.85E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed