BDBM50334597 5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-N4-(2-methoxy-4-morpholinophenyl)pyrimidine-2,4-diamine::CHEMBL1642255
SMILES COCCN1CCc2cc(Nc3ncc(Cl)c(Nc4ccc(cc4OC)N4CCOCC4)n3)c(OC)cc2CC1
InChI Key InChIKey=MKNXBDPSGZZPKP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50334597
Affinity DataIC50: 150nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of NPM-ALK autophosphorylation in human ALCL SUP-M2 cells after 2 to 3 hrs by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of baculovirus expressed GST-tagged human ALK cytoplasmic domain using PLCgamma as substrate after 15 mins by time-resolved fluorescence a...More data for this Ligand-Target Pair