BDBM50334606 2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimidin-2-ylamino)-8-methoxy-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-N,N-dimethylacetamide::CHEMBL1642265

SMILES COc1ccc(Nc2nc(Nc3cc4CCN(CC(=O)N(C)C)CCc4cc3OC)ncc2Cl)c(OC)c1

InChI Key InChIKey=YMVVZENKOZBFDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334606   

TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50:  189nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed