BDBM50334631 CHEMBL523189::N-(5-(4-(cyclopropylamino)-1-methyl-1H-pyrazolo[5,1-b]purin-7-yl)-2-fluorobenzyl)acetamide

SMILES CC(=O)NCc1cc(ccc1F)-c1cc2nc(NC3CC3)c3ncn(C)c3n2n1

InChI Key InChIKey=VBGRSDHDLOPNMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334631   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334631(N-(5-(4-(cyclopropylamino)-1-methyl-1H-pyrazolo[5,...)
Affinity DataIC50: 279nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334631(N-(5-(4-(cyclopropylamino)-1-methyl-1H-pyrazolo[5,...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed