BDBM50335502 4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sulfonate::CHEMBL1651849

SMILES CC(C)CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1

InChI Key InChIKey=NMRGHYQXKHANMB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335502   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  240nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335502(4-(Thiiran-2-ylmethylsulfonyl)phenyl propane-2-sul...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed