BDBM50335572 CHEMBL1650846::Methyl 1-{4-[2-(4-methylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctanecarboxylate

SMILES COC(=O)C1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)N1CCN(C)CC1

InChI Key InChIKey=JEJYQYUPGBHILH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335572   

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335572(Methyl 1-{4-[2-(4-methylpiperazin-1-yl)-1H-benzimi...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335572(Methyl 1-{4-[2-(4-methylpiperazin-1-yl)-1H-benzimi...)
Affinity DataKi:  312nMAssay Description:Displacement of [3H]DPDPE from human DOP receptor expressed in CHO-K1 cells after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335572(Methyl 1-{4-[2-(4-methylpiperazin-1-yl)-1H-benzimi...)
Affinity DataKi: >450nMAssay Description:Displacement of [3H]DAMGO from human MOP receptor expressed in CHO-K1 cells after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335572(Methyl 1-{4-[2-(4-methylpiperazin-1-yl)-1H-benzimi...)
Affinity DataKi: >570nMAssay Description:Displacement of [3H]enadoline from human KOP receptor expressed in HEK-293 cells after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed