BDBM50336420 4-amino-2-methyl-N-(1H-pyrazol-4-yl)quinazoline-8-carboxamide::CHEMBL1667869

SMILES Cc1nc(N)c2cccc(C(=O)Nc3cn[nH]c3)c2n1

InChI Key InChIKey=RDPWIYUOSKRMLU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336420   

LigandPNGBDBM50336420(4-amino-2-methyl-N-(1H-pyrazol-4-yl)quinazoline-8-...)
Affinity DataKi:  6nMAssay Description:Inhibition of PI3Kalpha by fluorescene polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336420(4-amino-2-methyl-N-(1H-pyrazol-4-yl)quinazoline-8-...)
Affinity DataKi:  21nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed