BDBM50336890 (+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylpropan-1-amine::CHEMBL1672374::US10913711, Compound 200::US11555013, Compound 200::US9862679, Compound 200

SMILES O=S(CCNCCCc1ccccc1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=QCMUGORVKCWDCX-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50336890   

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  1.00E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  1.00E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  1.00E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetTransporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetTransporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetTransporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institutes of Health

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed