BDBM50336996 CHEMBL1672631::N-[6-(2-Fluorophenyl)-5-(3-fluoropyridin-4-yl)pyrazin-2-yl]cyclopropane-carboxamide

SMILES Fc1ccccc1-c1nc(NC(=O)C2CC2)cnc1-c1ccncc1F

InChI Key InChIKey=SVYGTBODIFTCOZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336996   

TargetAdenosine receptor A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336996(N-[6-(2-Fluorophenyl)-5-(3-fluoropyridin-4-yl)pyra...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336996(N-[6-(2-Fluorophenyl)-5-(3-fluoropyridin-4-yl)pyra...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cells after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336996(N-[6-(2-Fluorophenyl)-5-(3-fluoropyridin-4-yl)pyra...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 90 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed