BDBM50337544 6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridin-2(1H)-one::CHEMBL1682838

SMILES CCN(CC)c1cc(cc(=O)n1C)-c1ccncn1

InChI Key InChIKey=YDSLUUMLFXCJOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337544   

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337544(6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridi...)
Affinity DataIC50:  50.1nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337544(6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridi...)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed