BDBM50337819 (1-(3,4-dichlorophenyl)cycloheptyl)methanamine::CHEMBL1683881::US10562878, Compound 4

SMILES NCC1(CCCCCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=NMFAKPRDDDKVBP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337819   

TargetSodium-dependent noradrenaline transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337819((1-(3,4-dichlorophenyl)cycloheptyl)methanamine | C...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337819((1-(3,4-dichlorophenyl)cycloheptyl)methanamine | C...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337819((1-(3,4-dichlorophenyl)cycloheptyl)methanamine | C...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337819((1-(3,4-dichlorophenyl)cycloheptyl)methanamine | C...)
Affinity DataIC50:  637nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337819((1-(3,4-dichlorophenyl)cycloheptyl)methanamine | C...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337819((1-(3,4-dichlorophenyl)cycloheptyl)methanamine | C...)
Affinity DataIC50:  637nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed