BDBM50337845 1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanamine::CHEMBL1683885::US10562878, Compound 84

SMILES CNCC1(CCCCC1)c1ccc(Cl)cc1

InChI Key InChIKey=HOXBFDRIDWJAEN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337845   

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337845(1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanami...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337845(1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanami...)
Affinity DataIC50:  326nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337845(1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanami...)
Affinity DataIC50:  395nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337845(1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanami...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337845(1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanami...)
Affinity DataIC50:  326nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337845(1-(1-(4-chlorophenyl)cyclohexyl)-N-methylmethanami...)
Affinity DataIC50:  395nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed