BDBM50338420 CHEMBL1683126::trans-3-(((4-((R)-1-amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)(methyl)amino)methyl)benzonitrile

SMILES CN(Cc1cccc(C#N)c1)[C@H]1CC[C@H]([C@H](N)Cc2cc(F)ccc2F)CC1

InChI Key InChIKey=HYRVBUOVRJKNRT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338420   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338420BDBM50338420(trans-3-(((4-((R)-1-amino-2-(2,5-difluorophenyl)et...)
Affinity DataIC50: 220nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338420BDBM50338420(trans-3-(((4-((R)-1-amino-2-(2,5-difluorophenyl)et...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338420BDBM50338420(trans-3-(((4-((R)-1-amino-2-(2,5-difluorophenyl)et...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338420BDBM50338420(trans-3-(((4-((R)-1-amino-2-(2,5-difluorophenyl)et...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338420BDBM50338420(trans-3-(((4-((R)-1-amino-2-(2,5-difluorophenyl)et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed