BDBM50338811 2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-isopropylacetamide::CHEMBL1684574

SMILES CC(C)NC(=O)Cn1c(nc2ccc(OCCCN3CCCCC3)cc2c1=O)-c1cccc(Cl)c1

InChI Key InChIKey=MOMPUOVKLQCIDO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50338811   

TargetVasopressin V1b receptor(Rat)
Msd

Curated by ChEMBL
LigandPNGBDBM50338811(2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in CHO cells by whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50338811(2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50338811(2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]AVP from human V1b receptor expressed in CHO cells co-expressing VIP-luciferase by whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50338811(2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]AVP from human vasopressin V1a receptor at 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50338811(2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]AVP from human vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetOxytocin receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50338811(2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed