BDBM50339041 CHEMBL1688250::N-((1,4-dioxan-2-yl)methyl)-3-(5-(4-(methylsulfonyl)phenyl)-4H-1,2,4-triazol-3-yl)pyridin-2-amine

SMILES CS(=O)(=O)c1ccc(cc1)-c1nnc([nH]1)-c1cccnc1NCC1COCCO1

InChI Key InChIKey=VPHZTEPWKIHNDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339041   

LigandPNGBDBM50339041(N-((1,4-dioxan-2-yl)methyl)-3-(5-(4-(methylsulfony...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of VEGFR-2 kinase assessed as phosphorylated level of pGAT-biotin peptide preincubated for 5 to 10 mins before addition of substrate measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339041(N-((1,4-dioxan-2-yl)methyl)-3-(5-(4-(methylsulfony...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed