BDBM50339061 4-(3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-7-yl)cyclobutyl)piperazine-1-carbaldehyde::CHEMBL1688360

SMILES Nc1ncnn2c1c(-c1ccc3ccc(-c4ccccc4)nc3c1)nc2[C@H]1C[C@@H](N2CCN(C=O)CC2)C1

InChI Key InChIKey=RDFZVFFSXWGAKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339061   

LigandChemical structure of BindingDB Monomer ID 50339061BDBM50339061(4-(3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,5...)
Affinity DataIC50: 26nMAssay Description:Inhibition of auto-phosphorylation of human IGF1R expressed in mouse NIH-3T3 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339061BDBM50339061(4-(3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,5...)
Affinity DataIC50: 260nMAssay Description:Inhibition of auto-phosphorylation of human IR expressed in human HepG2 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed