BDBM50339063 7-(3-(4-methylpiperazin-1-yl)cyclobutyl)-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-4-amine::CHEMBL1688362

SMILES CN1CCN([C@H]2C[C@@H](c3nc(-c4ccc5ccc(-c6ccccc6)nc5c4)c4c(N)ncnn43)C2)CC1

InChI Key InChIKey=CAXBBGZEJPMNQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339063   

LigandChemical structure of BindingDB Monomer ID 50339063BDBM50339063(7-(3-(4-methylpiperazin-1-yl)cyclobutyl)-5-(2-phen...)
Affinity DataIC50: 25nMAssay Description:Inhibition of auto-phosphorylation of human IGF1R expressed in mouse NIH-3T3 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339063BDBM50339063(7-(3-(4-methylpiperazin-1-yl)cyclobutyl)-5-(2-phen...)
Affinity DataIC50: 320nMAssay Description:Inhibition of auto-phosphorylation of human IR expressed in human HepG2 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed