BDBM50339169 CHEMBL1689401::N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22-((1H-indol-3-yl)methyl)-34-((S)-1-amino-3-hydroxy-1-oxopropan-2-ylcarbamoyl)-10-benzyl-16,28-bis(3-guanidinopropyl)-19-(4-hydroxybenzyl)-7-((R)-1-hydroxyethyl)-4,31-diisobutyl-13-(4-methacrylamidobutyl)-25-methyl-2,5,8,11,14,17,20,23,26,29,32-undecaoxo-3,6,9,12,15,18,21,24,27,30,33-undecaazaoctatriacontan-38-yl)-2-(4-methoxyphenyl)-2H-tetrazole-5-carboxamide

SMILES C=C(C)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)c1nnn(-c2ccc(OC)cc2)n1)C(=O)N[C@@H](CO)C(N)=O

InChI Key InChIKey=ZNRVSPZJPHWGPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339169   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339169BDBM50339169(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human GST-tagged Mdm2 expressed in Escherichia coli harboring integrated p53-Mmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339169BDBM50339169(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-22-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed