BDBM50339246 CHEMBL1689558::allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-1-(furan-2-yl)-12-(3-guanidinopropyl)-3,15-diisobutyl-1,4,7,10,13,16-hexaoxo-2,5,8,11,14,17-hexaazahenicosan-21-ylcarbamate

SMILES C=CCOC(=O)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)c1ccco1)[C@@H](C)CC)C(N)=O

InChI Key InChIKey=GFTAOAHWASTWGT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339246   

TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339246BDBM50339246(allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-...)
Affinity DataEC50:  138nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339246BDBM50339246(allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-...)
Affinity DataEC50:  840nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed