BDBM50339895 (S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)piperidin-3-yl)-3-ethyl-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1761298

SMILES CCn1c2ccccc2n([C@H]2CCCN(C2)c2ccnc(n2)-c2ccc(Cl)s2)c1=O

InChI Key InChIKey=NGYLGKJFTFTOSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339895   

TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339895((S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339895((S)-1-(1-(2-(5-chlorothiophen-2-yl)pyrimidin-4-yl)...)
Affinity DataIC50: 340nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed