BDBM50340119 CHEMBL1760033::N2-(quinolin-3-yl)-N4-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine

SMILES COc1cc(Nc2ncnc(Nc3cnc4ccccc4c3)n2)cc(OC)c1OC

InChI Key InChIKey=MTMFBNKTKJENJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340119   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340119(CHEMBL1760033 | N2-(quinolin-3-yl)-N4-(3,4,5-trime...)
Affinity DataIC50:  175nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340119(CHEMBL1760033 | N2-(quinolin-3-yl)-N4-(3,4,5-trime...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed