BDBM50340644 CHEMBL4169199

SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)N1C(=O)O[C@H](CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O

InChI Key InChIKey=UYMUWOSGPSGFAU-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50340644   

TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340644BDBM50340644(CHEMBL4169199)
Affinity DataIC50: 0.0160nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 assessed as inhibition forskolin-induced cAMP accumulation after 15 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340644BDBM50340644(CHEMBL4169199)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340644BDBM50340644(CHEMBL4169199)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in HEK293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340644BDBM50340644(CHEMBL4169199)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in HEK293 cell membranes after 2 hrs by liquid scintillation spectrometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed