BDBM50341430 CHEMBL4176704::US11534443, Example 8
SMILES Cc1nc(N)nc2c(OC3CCOCC3)cc(cc12)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1
InChI Key InChIKey=UBTCFPBWLDOPTP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50341430
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))
Institute of Materia Medica, Chinese Academy of Medical Sciences
US Patent
Institute of Materia Medica, Chinese Academy of Medical Sciences
US Patent
Affinity DataIC50: 1nMAssay Description:The Kinase-Glo™ Kinase Assay Kit was purchased from Promega. All assays were performed at room temperature using white OptiPlate™-384 well plate. The...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College
Curated by ChEMBL
Chinese Academy of Medical Sciences and Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate by Kinase-Glo assayMore data for this Ligand-Target Pair