BDBM50341551 (E)-N'-(Pyridin-2-ylmethylene)pyrrolidine-1-carbothiohydrazide::CHEMBL1765795

SMILES S=C(NN=Cc1ccccn1)N1CCCC1

InChI Key InChIKey=CDKSNQKTMAIJQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341551   

TargetDNA topoisomerase 2-alpha(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50341551((E)-N'-(Pyridin-2-ylmethylene)pyrrolidine-1-carbot...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pHOT DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed