BDBM50341720 3-amino-6-(2-(methylsulfinyl)phenyl)-N-phenylpyrazine-2-carboxamide::CHEMBL1766766

SMILES CS(=O)c1ccccc1-c1cnc(N)c(n1)C(=O)Nc1ccccc1

InChI Key InChIKey=FCWWTHQCXQLULC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341720   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50341720(3-amino-6-(2-(methylsulfinyl)phenyl)-N-phenylpyraz...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of DNAPK after 2 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine-protein kinase ATM(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50341720(3-amino-6-(2-(methylsulfinyl)phenyl)-N-phenylpyraz...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of full length recombinant ATM after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase ATR(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50341720(3-amino-6-(2-(methylsulfinyl)phenyl)-N-phenylpyraz...)
Affinity DataIC50:  130nMAssay Description:Inhibition of full length recombinant ATR after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed