BDBM50342695 4-methyl-6-(1'-(5-methylpyrazin-2-yl)-4,4'-bipiperidin-1-yl)pyrimidine-2-carbonitrile::CHEMBL1771096

SMILES Cc1cnc(cn1)N1CCC(CC1)C1CCN(CC1)c1cc(C)nc(n1)C#N

InChI Key InChIKey=PGXPWGAAHUNTQI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342695   

LigandPNGBDBM50342695(4-methyl-6-(1'-(5-methylpyrazin-2-yl)-4,4'-bipiper...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342695(4-methyl-6-(1'-(5-methylpyrazin-2-yl)-4,4'-bipiper...)
Affinity DataEC50:  64nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342695(4-methyl-6-(1'-(5-methylpyrazin-2-yl)-4,4'-bipiper...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed