BDBM50342696 (rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperidin-4-yl)cyclopropyl)methoxy)-N-cyclopropyl-2-fluorobenzamide::(rac)-trans-4-((2-(1-(5-chloropyrimidin-2-yl)piperidin-4-yl)cyclopropyl)methoxy)-N-cyclopropyl-2-fluorobenzamide::CHEMBL1771097

SMILES Fc1cc(OCC2CC2C2CCN(CC2)c2ncc(Cl)cn2)ccc1C(=O)NC1CC1

InChI Key InChIKey=RWBWCXVARSSZKV-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342696   

LigandPNGBDBM50342696((rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperid...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342696((rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperid...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342696((rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperid...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342696((rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperid...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342696((rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperid...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342696((rac)-cis-4-((2-(1-(5-chloropyrimidin-2-yl)piperid...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed