BDBM50342708 3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one::CHEMBL1771114

SMILES COc1ccccc1N1CCN(CCCCN2CCc3cc(ccc3C2=O)C#C)CC1

InChI Key InChIKey=XKAIELUQYYUCFN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50342708   

TargetD(3) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342708(3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)pip...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342708(3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)pip...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342708(3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)pip...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Pig)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342708(3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)pip...)
Affinity DataKi:  920nMAssay Description:Displacement of [3H]Ketanserin from pig 5-HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Pig)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342708(3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)pip...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptor in pig striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed