BDBM50342738 3-Cyano-4-phenyl-N-(1-[2-chlorophenyl]-3-phenyl-1H-pyrazol-5-yl)benzamide::CHEMBL1771271

SMILES Clc1ccccc1-n1nc(cc1NC(=O)c1ccc(-c2ccccc2)c(c1)C#N)-c1ccccc1

InChI Key InChIKey=OAXZPTTYXBVVPR-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342738   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50342738(3-Cyano-4-phenyl-N-(1-[2-chlorophenyl]-3-phenyl-1H...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-MPEP from mGluR5 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50342738(3-Cyano-4-phenyl-N-(1-[2-chlorophenyl]-3-phenyl-1H...)
Affinity DataEC50:  4.14E+3nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed