BDBM50342910 6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylthiazol-4-yl)methyl)quinazolin-4-amine::CHEMBL1435542
SMILES Cc1nc(CNc2ncnc3ccc(cc23)-c2ccc3OCOc3c2)cs1
InChI Key InChIKey=LELRIWOVACJYND-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50342910
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 280nMAssay Description:Binding affinity to human PIP5K2C More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 380nMAssay Description:Binding affinity to human Clk2 More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to human Clk4 More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 50nMAssay Description:Binding affinity to human Clk1 More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 82nMAssay Description:Binding affinity to human Dyrk1A More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair