BDBM50343320 CHEMBL1774228::cis-1-methyl-2-(((3S,4S)-3-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine

SMILES C[C@@H]1CN(Cc2nc3ncccc3n2C)CC[C@@H]1c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IORJDNYKXIMYCK-PBHICJAKSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343320   

TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343320(CHEMBL1774228 | cis-1-methyl-2-(((3S,4S)-3-methyl-...)
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343320(CHEMBL1774228 | cis-1-methyl-2-(((3S,4S)-3-methyl-...)
Affinity DataEC50: >1.99E+3nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed