BDBM50343374 2-amino-N-cyclobutyl-4-(2,4-dichloro-6-(3-cyanopropoxy)phenyl)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxamide::CHEMBL1774912

SMILES Nc1nc2CN(Cc2c(n1)-c1c(Cl)cc(Cl)cc1OCCCC#N)C(=O)NC1CCC1

InChI Key InChIKey=PAECAVLPKKKHNM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343374   Sort by

TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343374(2-amino-N-cyclobutyl-4-(2,4-dichloro-6-(3-cyanopro...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed