BDBM50343379 2-Amino-4-[2,4-dichloro-6-(2-ethylamino-ethoxy)-phenyl]-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid cyclobutylamide::CHEMBL1774917

SMILES CCNCCOc1cc(Cl)cc(Cl)c1-c1nc(N)nc2CN(Cc12)C(=O)NC1CCC1

InChI Key InChIKey=APFZLEILTRYZRY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343379   Sort by

TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343379(2-Amino-4-[2,4-dichloro-6-(2-ethylamino-ethoxy)-ph...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed