BDBM50343529 2-(6-(4-tert-butylbenzamido)benzo[d]thiazol-2-ylthio)pentanoic acid::CHEMBL1774308

SMILES CCCC(Sc1nc2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2s1)C(O)=O

InChI Key InChIKey=PEEFSAUDUBUYEP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343529   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343529(2-(6-(4-tert-butylbenzamido)benzo[d]thiazol-2-ylth...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant 5-LO in cell-free system assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343529(2-(6-(4-tert-butylbenzamido)benzo[d]thiazol-2-ylth...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343529(2-(6-(4-tert-butylbenzamido)benzo[d]thiazol-2-ylth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production after 10 mins by RP-HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed