BDBM50343535 3-(1-(4-chlorobenzyl)-3-(benzylthio)-5-(2-(4-chloro-2-fluorophenyl)ethynyl)-1H-indol-2-yl)-2,2-dimethylpropanoic acid::3-(3-(benzylthio)-5-((4-chloro-2-fluorophenyl)ethynyl)-1-(4-chlorobenzyl)-1H-indol-2-yl)-2,2-dimethylpropanoic acid::CHEMBL509791

SMILES CC(C)(Cc1c(SCc2ccccc2)c2cc(ccc2n1Cc1ccc(Cl)cc1)C#Cc1ccc(Cl)cc1F)C(O)=O

InChI Key InChIKey=WMQNBFQWQZXFQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343535   

TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343535(3-(1-(4-chlorobenzyl)-3-(benzylthio)-5-(2-(4-chlor...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed