BDBM50343539 5-(4-tert-butylbenzyl)-3-(4-isopropoxyphenyl)-1-(4-(isopropylamino)phenyl)-1H-indole-2-carboxylic acid::CHEMBL453202

SMILES CC(C)Nc1ccc(cc1)-n1c(C(O)=O)c(-c2ccc(OC(C)C)cc2)c2cc(Cc3ccc(cc3)C(C)(C)C)ccc12

InChI Key InChIKey=LEPNSTRNLOWFCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343539   

TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343539(5-(4-tert-butylbenzyl)-3-(4-isopropoxyphenyl)-1-(4...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed