BDBM50343894 CHEMBL1774995::N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-iodo-N-(pyridin-2-yl)cubyl-1-carboxamide

SMILES Oc1ccccc1N1CCN(CCN(C(=O)C23C4C5C2C2C3C4C52I)c2ccccn2)CC1

InChI Key InChIKey=IUEHDTRLKKNLDW-UHFFFAOYSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50343894   

Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 EBNA cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  25nMAssay Description:Inhibition of adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  50nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  176nMAssay Description:Inhibition of adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  181nMAssay Description:Inhibition of adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  272nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50343894(N-(2-(4-(2-Hydroxyphenyl)piperazin-1-yl)ethyl)-4-i...)
Affinity DataKi:  890nMAssay Description:Inhibition of dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed