BDBM50344162 (R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclopentanecarboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1778388

SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)C1(CCCC1)c1ccc(F)cc1

InChI Key InChIKey=UPZGABGQGJFIDG-HXUWFJFHSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50344162   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344162((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclopentanec...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human CRTH2 receptor expressed in HEK293-EBNA cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344162((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclopentanec...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344162((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclopentanec...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst

Curated by ChEMBL
LigandPNGBDBM50344162((R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclopentanec...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK293-EBNA cells assessed as inhibition of forskolin-stimulated intracellular cAMP producti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed