BDBM50344327 2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]pyridin-4-yl)pyridazin-3(2H)-one::CHEMBL1779445

SMILES COc1ccc(-c2ccc(=O)n(Cc3ccccc3)n2)c2cc(nn12)C(C)C

InChI Key InChIKey=KWDQBWJHNXTHPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344327   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344327(2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]py...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human PDE4B catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344327(2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]py...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human PDE5A catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344327(2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]py...)
Affinity DataIC50: 4.15E+4nMAssay Description:Inhibition of human PDE3A catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed