BDBM50344527 4-(2-(4-isopropylphenylamino)benzo[d]thiazol-5-yloxy)-N-methylpicolinamide::CHEMBL1778408

SMILES CNC(=O)c1cc(Oc2ccc3sc(Nc4ccc(cc4)C(C)C)nc3c2)ccn1

InChI Key InChIKey=RMQLQVJFCNMQCX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344527   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50344527(4-(2-(4-isopropylphenylamino)benzo[d]thiazol-5-ylo...)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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